Crabtree caught four passes for 70 yards on San Francisco's opening drive.

"If my life depended on it and someone had to catch a ball, I'd enlist Michael Crabtree to do it," a well-amped Harbaugh said, adding that "Michael Crabtree ... he catches everything."

NOTES: Packers LT David Bahktiari (concussion) was replaced by Marshall Newhouse in the fourth quarter. ... 49ers LB Aldon Smith (muscle cramps) left the game in the first half but returned in the third quarter and recorded a quarterback sack. ... The 49ers' four regular-season losses were to teams still alive in the postseason (Seattle, Indianapolis, Carolina, New Orleans). ... Packers CB Sam Shields was assisted to the sideline by trainers and taken to the locker room on a cart with a knee injury on the 49ers' first offensive possession. He was replaced by second-year CB Davon House. ... Packers OLB Clay Matthews (thumb) and 49ers CB Carlos Rogers (hamstring) were inactive. ... OLB Mike Neal (knee) left for Green Bay after the first defensive series. OLB Andy Malumba (knee) left the game briefly in the third quarter. Because of the personnel shortage, defensive coordinator Dom Capers briefly used four down linemen. ... 49ers PK Phil Dawson kicked a 22-yard field goal to cap San Francisco's first drive. The 49ers outscored opponents 46-0 this season on game-opening drives.