Packers coach Mike McCarthy says Pro Bowl linebacker Clay Matthews will miss at least a couple weeks with a thumb injury.
McCarthy said Wednesday that Matthews may have to play with a cast when he returns. He says it could be "multiple weeks" overall.
Matthews was hurt last weekend against the Lions.
He has also been bothered by a sore hamstring. A hamstring injury sidelined Matthews for four games last season.
The Packers play the Ravens on Sunday in Baltimore. Nick Perry and Mike Neal figure to start on the outside with Matthews out.
Neal had six tackles and a sack last week in his first start at linebacker opposite Matthews.