GREEN BAY, Wis. -

The San Francisco 49ers can toss their film from the season opener against Green Bay in the trash for as much good as it will do now.

Cedric Benson is gone, and the Packers' running game is now being powered by DuJuan Harris and Ryan Grant. Randall Cobb, whose 75-yard punt return gave the Packers a fleeting chance late in the 30-22 victory by San Francisco, is now one of Aaron Rodgers's favorite receivers.

And a defense that may as well have been holding rookie orientation for all its newcomers is now a savvy, stingy bunch of veterans.

"A lot's happened," coach Mike McCarthy said. "We're a different football team. We're a different football team than we were four weeks ago."

The Packers (12-5) play San Francisco (11-4-1) Saturday night in an NFC divisional game.