Ohio State outgained Buffalo 460-258 in total yards.
"When you score 40 points and gain 460 yards or something like that and you're disappointed, that's a good sign," Meyer said. "But we've got a long way to go."
NOTES: Ohio State All-Big Ten linebacker Ryan Shazier went to the locker room in the first half with cramps but returned in the third quarter. He still led the team with 6 1/2 tackles. ... Buckeyes starting safety C.J. Barnett missed the game with a lower leg injury. ... Ohio State defensive lineman Tommy Schutt is out six to eight weeks with a broken foot. Chase Farris moved from the offensive line to defensive line this week to add depth. ... Buffalo defensive coordinator Lou Tepper is quite familiar with Ohio State, having faced the Buckeyes while he was coach at Illinois from 1991 to 1996. Tepper's teams beat Ohio State twice, but his 1995 Fighting Illini gave up 314 yards rushing to Heisman Trophy winner Eddie George. ... Buffalo's final game last season also was in Columbus. The Bulls lost to Bowling Green during Thanksgiving weekend at Crew Stadium, home of Columbus' Major League soccer team. ... Ohio State and Buffalo met for the first time in history. ... Ohio State last lost a season opener in 1999.