Milwaukee got two runs back in the third on Braun's RBI double and Ramirez's run-scoring single, but the Reds pulled away in the bottom half.
Cincinnati's spree included Latos' RBI groundball single up the middle through a drawn-in infield.
Aoki added his fourth homer of the season in the sixth.
NOTES: The win clinched the three-game series for the Reds, giving them six wins in seven home series this season. ... Reds OF Chris Heisey is scheduled to start a rehab assignment Monday at Double-A Pensacola. Heisey has been on the disabled list since April 29 with a strained right hamstring. ... For the first time in franchise history, the Reds wore red jerseys with "Los Rojos" written in script across the front. ... Aoki's strikeout leading off the game snapped at 37 his streak of consecutive plate appearances without fanning. ... RHP Bronson Arroyo (2-4) starts Sunday's series finale for the Reds against RHP Wily Peralta (3-2).