Romania will also be in the mix after taking second place in Group D.
Romania saw off Estonia 2-0 and benefited from Turkey's home defeat by a Netherlands side which had already qualified.
Meanwhile, Iceland booked its place in the playoffs following a 1-1 draw in Norway.
Kolbeinn Sigþórsson gave the visiting side the lead and although Norway did equalize, it could not prevent Iceland from finishing second in Group E.
Only Slovenia could have prevented Iceland from finishing second but it succumbed to a 1-0 defeat in Switzerland.
Russia qualified following a 1-1 draw in Azerbaijan meaning that Portugal's 3-0 win over Luxembourg was superfluous.
In the night's other games, Croatia was beaten 2-0 in Scotland, Belgium was held to a 1-1 draw by Wales and Germany edged out Sweden 5-3 in a thrilling contest.
In Africa, Ghana took a giant stride towards the World Cup following a crushing 6-1 win over Egypt in the first leg of its playoff tie.
Asamoah Gyan scored twice, while further strikes from Abdul Majeed Waris, Sulley Muntari, Christian Atsu and an own-goal sealed the win.