MADISON, Wis. -

One of the most popular animals at the Henry Vilas Zoo has died from cancer.

The 16-year-old lion, named Vilas, died after cancer spread from her mammaries to her lymph nodes.

She came to the zoo in 1997, along with a male lion, Henry.

Vilas had eight cubs, including her most recent, Leo, who was born in December 2010, and is still at the zoo.

Zookeepers are now working to find a new female lion to be with Henry.