CNN: It's been reported that you're working on a historical film, where you play Ulysses S. Grant. How far along is that?

Lowe: It's a big, expensive miniseries. Sony will be making it. I think the latest incarnation will be in conjunction with Reelz. It's something I've been attached to and wanting to do for a couple of years now. We're still waiting for the final OK, and I'm hoping it's a project I'd do on my hiatus, and it would be a dream project for me to play Ulysses S. Grant. He's a very underserved American hero and complicated, dark, flawed. When he died, America gave him the largest public funeral this country had ever seen. He saved the Union. I'm hopeful that'll happen.

CNN: Are you shooting anything else this year?

Lowe: I have a movie coming out in May with Steven Soderbergh directing and Michael Douglas and Matt Damon called "Behind the Candelabra." It's the story of Liberace.

Matt Damon and I would sit on the set in our makeup and costume and be like, "Dude, when people see us in this movie, it's going to be the end for both of us." It's the most outrageous, over-the-top, hilarious, demented and yet weirdly realistic and sweet movie ever made. And, I might add, it's so gay, it makes an average episode of "Glee" look like "The Expendables."